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Progress in Brain Research Vol.196

The latest volume from the book series Progress in Brain Research is entitled “Optogenetics: Tools for Controlling and Monitoring Neuronal Activity”, gathering 12 chapters of about 20 pages each. The volume is edited by Thomas Knöpfel and Edward S. Boyden and chooses to embed monitoring and controlling strategies into a unique, comprehensive concept of optogenetics, as explicited in the introductory chapter.

Table of Contents:

Chapter 1: A comprehensive concept of optogenetics. Chapter 2: Optogenetic excitation of neurons with channelrhodopsins: Light instrumentation, expression systems, and channelrhodopsin variants. Chapter 3: Genetically encoded molecular tools for light-driven silencing of targeted neurons. Chapter 4: Genetically encoded probes for optical imaging of brain electrical activity. Chapter 5: Neural activity imaging with genetically encoded calcium indicators. Chapter 6: Manipulating cellular processes using optical control of protein–protein interactions. Chapter 7: Two-photon optogenetics. Chapter 8: Zebrafish as an appealing model for optogenetic studies. Chapter 9: Genetic targeting of specific neuronal cell types in the cerebral cortex. Chapter 10: Mouse transgenic approaches in optogenetics. Chapter 11: Optogenetics in the nonhuman primate. Chapter 12: Optogenetic reporters: Fluorescent protein-based genetically encoded indicators of signaling and metabolism in the brain.

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